NAD+ Available in 60 Count Vegetarian Capsules NAD+ by Nutritional Frontiers is ideal for patients focused on energy restoration, metabolic efficiency, healthy aging, and neurological resilience. This formula is designed to complement protocols focused on mitochondrial support, detoxification, immune modulation, and metabolic repair.

NAD+ is a targeted formula designed to support mitochondrial function, healthy aging, and cellular metabolism through advanced nutrient delivery. This product combines 250 mg of ß-Nicotinamide Adenine Dinucleotide (NAD) with 250 mg of CurcuWIN®, a highly bioavailable turmeric extract standardized to curcuminoids. Together, these ingredients promote oxidative metabolism, support DNA repair mechanisms, modulate inflammatory signaling, and enhance cellular resilience to age-related stress. This synergistic formula is ideal for patients seeking metabolic restoration, cognitive support, or anti-aging interventions backed by emerging clinical science.

This unique formula contains researched ingredients to:

• Support mitochondrial energetics and cellular resilience
• Promote healthy collagen synthesis and connective-tissue repair
• Aid joint comfort, mobility, and workout recovery
• Nurture skin elasticity, hair, and nail strength
• •Enhance digestive tolerance and nutrient utilization

Collagen-rich tissues (joint cartilage, tendons, ligaments, fascia, skin, GI lining) rely on a steady supply of bioavailable peptides. Key collagen amino acids—glycine, proline, and hydroxyproline—also participate in cellular energy pathways (e.g., methylation and antioxidant systems that protect mitochondria). Collagen-5 combines five complementary collagen sources with targeted digestive enzymes and a robust, spore-forming probiotic to improve breakdown, absorption, and everyday GI comfort—so the body can use peptides where they’re needed most.

Hydrolyzed Bovine Collagen

Highly bioavailable peptides rich in glycine, proline, and hydroxyproline to support collagen rebuilding in skin, joints, and connective tissues. These amino acids help maintain mitochondrial-friendly redox balance (via glutathione and related pathways), aiding cellular resilience during physical and oxidative stress. Also supports tendon/ligament strength and post-exercise recovery.

Bovine Bone Broth

Naturally provides collagen peptides plus glycosaminoglycans (GAGs) and trace minerals that complement hydrolyzed collagen for joint and cartilage nourishment and GI mucosal support.

Eggshell Membrane Collagen

A unique matrix supplying collagen (types I, V, X), elastin, and GAGs to support joint comfort, flexibility, and tendon integrity. Works synergistically with type I/III peptides for comprehensive connective-tissue coverage.

NATICOL® Premium Fish Collagen

A low-molecular-weight type I marine collagen known for excellent bioavailability. Supports skin elasticity, dermal hydration, and fine-line appearance while complementing bovine and eggshell sources for a broader peptide profile.

Type II Collagen (Chicken)

Targets articular cartilage needs. Type II collagen helps maintain joint cushioning, range of motion, and everyday comfort, rounding out a multi-type approach (I/II/III/V/X) for whole-body connective-tissue support.

Prohydroxy Enzyme Blend

(Amylases, Lactase, Lipase, Protease I, Protease II) Multienzyme complex designed to improve protein and peptide.

This unique, SPM omega-3 derived supplement was designed to help modulate and resolve inflammation. SPM stands for "Specialized Pro-resolving Mediators" which are recently discovered, naturally occurring substances derived from omega-3 and omega-6 fatty acids. Our bodies make SPMs as a response to help resolve inflammation and they can be produced all over the body in areas like the bloodstream, nervous system tissue, and breastmilk. Specialized pro-resolving mediators are theorized to contribute to the demonstrable beneficial effects of omega-3 fatty acids on reducing inflammation.

The inflammatory process consists of a chain of events in response to trauma or injury. Inflammation may be acute or chronic and leads to changes in the tissues, cells, and blood vessels surrounding the inflamed area. While acute inflammation is a necessary and important response to trauma or injury, ongoing inflammation is associated with many disease conditions such as arthritis, autoimmune diseases, cardiovascular disease, asthma, Crohn's disease and ulcerative colitis, and more. Furthermore, the medical community now understands that uncontrolled inflammation is involved in the pathogenesis of many diseases not previously categorized as inflammatory, such as Alzheimer's disease, Parkinson's disease, and cancer.

SPMs do not block the vital initial inflammatory response to trauma, but rather SPMs prevent excessive inflammation and promote tissue homeostasis (return to normal functioning) by controlling the duration and magnitude of inflammation. They are called 'resolving mediators' because of their role in facilitating natural resolution of the inflammatory response. Examples of SPMs include resolvins, lipoxins, protectins, and maresins. SPMs have demonstrated potent immunoregulatory and anti-inflammatory activities such as inhibiting the production of pro-inflammatory mediators and regulating white blood cells. In addition to actively resolving inflammation, SPMs protect organs and stimulate tissue regeneration.

Research shows that SPM levels in the body are associated with reduced pain scores in patients with knee arthritis. Furthermore, erythrocyte sedimentation rates (ESR), a blood test marker for inflammation, were also reduced in those patients with arthritis taking SPM. Many animal studies demonstrate improved healing rates in conditions like colitis, ischemic kidney damage, periodontitis, and asthma.

While SPMs are produced naturally in humans, the ability of the body to produce SPMs may be compromised in the setting of obesity and aging. Since SPMs are involved in the active, regulated process of resolving acute inflammation and managing the return to tissue homeostasis, supplementing with SPMs may provide benefit and relief to those individuals struggling with discomfort and prolonged inflammation.*