PSA contains a combination of nutrients and herbs to promote proper function of the prostate gland.* The prostate is a walnut-sized gland that plays a role in male reproduction. Many men over age 50 have some prostate enlargement, called BPH - benign prostatic hyperplasia. The enlarged gland causes obstructive symptoms like urinary frequency, urgency, and even sometimes urinary incontinence. The Nutritional Frontiers’ supplement PSA was designed to be helpful for balancing hormones, managing DHT levels, and positively affecting the enzymes that support healthy prostate size and function.

Zinc is a mineral with a myriad of uses in the body. The prostate gland has the highest concentration of zinc in the body and requires 10 times more zinc than any other organ. Zinc supplementation also may help inhibit 5-alpha reductase. Vitamin B-6 (pyridoxal-5-phosphate) may aid in the utilization of zinc.

Saw palmetto, also called Serenoa repens, is a plant native to the Caribbean Islands and the Southeastern USA. Serenoa contains flavonoids, fatty acids, and sterols which inhibit 5-alpha-reductase, an enzyme that converts testosterone to its more active form, DHT. Therefore, saw palmetto has been used effectively in people with prostate disease and PCOS or other conditions with elevated testosterone levels.

Phytosterol Complex (Beta-sitosterol), a compound derived from plants, has a similar action of inhibiting the enzyme that produces DHT. Beta-sitosterol may improve urinary residual volume and urinary flow in men with BPH though according to research so far, it has not been demonstrated in research to actually reduce prostate size.

Pumpkin Seed Powder Extract, research suggests, may help with overactive bladder, a condition characterized by a sudden urge to urinate that may lead to an involuntary loss of urine. Researchers estimate that 16% of men and women suffer from overactive bladder symptoms such as urination urgency as well as frequent daytime and night urination. Several studies have shown compelling data in pumpkin seed extract’s ability to support bladder function and combat the symptoms associated with an overactive bladder. In an animal study published in the Japanese Journal of Medicine and Pharmaceutical Science, rats supplemented with pumpkin seed extract significantly improved bladder function and decreased urinary frequency.

Green tea comes from the same plant as black tea: Camellia sinensis. Green tea, unlike black tea, is not fermented after being picked therefore the active components of the herb remain unchanged. Because of its roles as a powerful antioxidant, green tea is included here to support detoxification. Furthermore, drinking tea (and possibly other caffeinated beverages) may influence serum concentrations of a protein called sex hormone binding globulin (SHBG), which binds circulating hormones like DHT.

DIM is a compound derived from cruciferous vegetables like broccoli and Brussels sprouts. DIM competes with DHT (active testosterone) for binding at testosterone receptors. DIM also plays a role in estrogen metabolism and may cause a beneficial shift in the balance of estrogen, testosterone, and progesterone. Inadequate estrogen metabolism is associated with hormonal imbalance in both sexes.

· Stinging nettle (Urtica dioica) is a nutritious plant historically used as medicine and food. The leaf, root and seeds all possess medicinal benefits. Like saw palmetto and Pygeum, nettles root may also block the action of 5-alpha-reductase and thereby reduce the effects of excess testosterone in the body. Some case studies and clinical trials show improvement of BPH symptoms from use of nettles. Nettles combined with saw palmetto was shown in studies to be as effective as the prostate medication finasteride, with fewer side effects! The study participants noted improved urinary flow, quality of life, and erectile function. Another study combining saw palmetto with nettles root in elderly men with BPH and related urinary symptoms showed reduction of urinary symptoms.

Pygeum africanum bark comes from an evergreen tree found in southern and central Africa. Several positive clinical trials have been conducted in Europe and a majority of trials show benefits of taking Pygeum on frequency of nocturia (night-time urination that interferes with sleep), urine flow rate, & residual urine volume. Pygeum bark may help control the activity of the testosterone - producing enzyme 5-alpha-reductase, especially when combined with nettles. Therefore, they can help balance the ratio of testosterone & estrogen in the body.*

Lycored lycopene™ is a proprietary tomato extract containing lycopene. Lycopene is red carotenoid concentrated in the human body in serum, liver, adrenal glands, lungs, prostate, colon, and skin. It is one of 600+ known carotenoids, which are fat-soluble hydrocarbon pigments responsible for the orange, red, yellow colors in fruits, veggies, birds, fish, and crustaceans. Lycopene may help control prostate gland size in part by inhibiting DNA synthesis in primary prostate epithelial cells. Lycopene is a powerful antioxidant, protecting cells from oxidative stress, as well as inhibiting cell proliferation.

Estrocleanse III is a unique antioxidant formulation designed to enhance detoxification and promote hormone balance in both men and women.

The sex hormones include estrogen (which includes several types), progesterone, and testosterone. Certain types of estrogen are considered to be more beneficial than other types, and healthy metabolism of estrogen is associated with fewer health risks. Estrogen is produced in both women and men, and inadequate estrogen metabolism is associated with hormonal imbalance in both sexes. I3C and DIM can improve estrogen metabolism. I3C is known to improve the ratio of estrogen types.

Benefits:

Calcium D-Glucarate glucaric acid is found in our bodies as well as in fruits and vegetables such as oranges, apples, brussel sprouts, broccoli, and cabbage. Calcium D-glucarate might lower estrogen levels, and this is thought to be helpful in supporting some people with hormone deficiencies.

CurcuWIN™ Turmeric Extract is derived from the spice turmeric. It scavenges free radicals and also may have an indirect antioxidant effect by stimulating the synthesis of glutathione. CurcuWIN™ also has the reputation of being antiinflammatory and protective of the digestive tract. Many in vitro studies show that curcumin may support immune function.

Green tea (and its active polyphenolic component EGCG) is derived from the same plant as black and oolong teas: Camellia sinensis. Green tea, unlike black and oolong tea, is not fermented after being picked therefore the active components of the herb remain unchanged. Green tea is an antioxidant, stimulates detoxification, improves the lipid profiles, and has immune-stimulating effects.

Resveratrol is a polyphenolic compound most associated with grapes, red grape juice, and red wine. It is also said to improve cardiovascular health and improve blood flow to the brain.

DIM is a plant-derived compound that enhances estrogen metabolism causing a beneficial shift in the balance of estrogen, testosterone, and progesterone in men and women. Hormone balance is necessary for prostate, ovarian, uterine, cervical, and breast health.

Indole 3 carbinol (I3C) is a phytochemical found naturally in cruciferous vegetables like broccoli, cabbage, brussel sprouts, and kale. I3C is closely related to DIM, as I3C is transformed by the action of stomach acid into DIM. I3C and DIM increase the activity of certain liver enzymes which can help to eliminate toxins and carcinogens.

i-Sabi™ is a natural dietary ingredient made from the rhizomes of pure Wasabia japonica. i-Sabi™ provides a full spectrum of ITCs that supports your immune system, detoxifies and maintains healthy liver function, and provides strong antioxidant activity for cellular health.

Tocotrienols are members of the vitamin E family of nutrients. Tocotrienols possess antioxidant properties against lipid peroxidation. Therefore they are used in the prevention of atherosclerosis and maintaining a healthy cardiovascular system.

Bioperine® (black pepper fruit extract) is thought to enhance the absorption of other nutrients, like curcumin, into the bloodstream. Some studies have shown that Bioperine can increase Curcumin absorption by over 30%.

Frontier Multivitamin by Nutritional Frontiers is a new, improved, high quality multivitamin-mineral supplement designed for adults. The easy-to-swallow vegetarian capsules provide more than 50 vitamins, minerals, antioxidants, and other nutrients in bioavailable forms and nutritionally meaningful amounts.

A complete multivitamin provides important antioxidant vitamins A, C and E, an array of B vitamins, easily absorbable calcium and magnesium, as well as a full spectrum of bioavailable, trademarked TRAACS minerals and trace elements, along with choline, a super food ORAC blend, CoQ10, Lutemax, and red beet powder. Supplementing with red beet root was shown in a 2016 study to reduce blood pressure, cholesterol, and the inflammatory marker hsCRP.

Benefits:

Vitamin D has been added to this formula, as research indicates that people do not receive enough of this nutrient due to reduced sun exposure and limited dietary sources. Vitamin D plays many roles in the body and is vital for supporting strong, healthy bones.

Optimal Forms of Nutrients, Vitamin B12, and Folate are included in Frontier Multivitamin. This multivitamin provides Vitamin B12 as methylcobalamin. Most multi’s contain cyanocobalamin, a form of B12 which is cheaper and not as well utilized by the body.

Antioxidant Defense is an important component of a superior multi. Glutathione is the master antioxidant that is synthesized inside the body. Selenium, vitamin C and N-Acetyl Cysteine are precursors to glutathione synthesis. Furthermore our new multivitamin contains an antioxidant spectrum of CoQ10, Vitamin E, Beta Carotene, green tea, Lutemax (lutein in its natural ester form), Lycopene, and a high ORAC super food blend.

Citrus bioflavonoids, lemon bioflavonoids, and vitamin C have been included to support the immune system, capillary and connective tissue health.* Bioflavonoids increase the effectiveness of Vitamin C by 50%.

Bone Health vitamins and minerals such as, calcium, magnesium, boron, Vitamin D, and zinc have been included to support bone strength and density.

Cardiac Health is supported by red beet powder, lutein, zeaxanthin, beta carotene, Vitamin E, magnesium, lycopene, potassium, and CoQ10. Specifically, the carotenoids like lutein, beta carotene, zeaxathin, and lycopene reduce reactive oxygen species (ROS) which can help reduce atherosclerosis. For homocysteine management, B6, B12 and folate are added to support methylation and the recycling of homocysteine. Immune system support is provided by Vitamins A, C, B6, E, Folate, and Zinc.

Eye Health support is provided by lutein (as Lutemax), vitamin E, and zeaxanthin, which are well-studied nutrients for ocular function.

Nutritional Frontiers does not use any additives or preservatives like corn starch, talc, crospovidone, hydrogenated oil, food colorings, polyethylene glycol, polyvinyl alcohol, & BHT.

Frontier Cleanse is a gluten free dietary supplement designed to help balance, soothe and replenish the Gastro Intestinal Tract.

A Balance & Capture Blend containing Soluble Fiber (Fibersol-2™ Brand), Psyllium Seed Husk, FOS (Fructooligosaccharides), Flax Seed Meal and Apple Pectin to support regularity, the immune system and healthy microbial balance.

A Soothe & Replenish Blend containing N-Acetyl Glucosamine, L-Glutamine, Peppermint, Chamomile, Aloe Leaf Powder, Horsetail Rush, Rosemary and Ginger Root Powder to nourish and soothe the GI Tract as well as support overall function.

A Reds & Greens Blend containing Alfalfa Powder, Spirulina, Beet Juice Powder, Chlorella-Cracked Cell Powder, Parsley Juice Powder, Broccoli Powder, Red Raspberry Powder, Acerola Berry Juice Powder, Cranberry Juice Powder, Watercress and Blessed Thistle for detoxification, energy and to reduce oxidative stress.

A Remove & Detox Blend containing Arabinogalactans, Bentonite Clay, Olive Leaf Extract, Black Walnut (Green Hull) Powder, Kelp, Artichoke, Burdock, Garlic and Dandelion Root

Nutrients of Interest:

Aloe helps to support healing of the lining of the stomach and keep the folds and pockets of the colon free of toxic material that gather there.

Arabinogalactans support colon health by acting as a fermentable fiber to promote growth of probiotic bacteria such as Lactobacillus and Bifidobacteria in the colon. They also work in the GI tract by activating immune cells.

Artichoke promotes the flow of bile. Good bile flow is also necessary for detoxification which is carried out by the liver. Bile serves as a carrier for the toxins that are excreted by the liver which are then sent to the intestine for their exit from the body.

Bentonite Clay is natural clay used for detoxification of toxins and unwanted material. Bentonite also helps clean the colon by scraping the lining of the colon thereby freeing it of the various wastes deposited by years of eating an unhealthy diet.

Burdock promotes the flow and release of bile, which helps to cleanse the liver. It also aids the digestive process. The mucilage, “bitter” and inulin contents in Burdock also help to support good digestion, as well as soothe the digestive tract.

Chlorella supports cell reproduction, as well as restorative processes that promote healthy organs and tissues. Chlorella also aids the body in the breakdown of unwanted materials like heavy metals, and supports proper digestion by promoting the growth of beneficial bacteria and assisting in the elimination of unwanted materials from the body.

N-Acetyl Glucosamine improves the integrity of the mucosal lining.

Fibersol-2™ is a soluble fiber that has been shown to support proper bowel function, regularity, fecal volume, beneficial micro flora as well as a clean and healthy digestive tract.

FOS (Fructooligosaccharides) aids in the elimination of unwanted substances and supports G.I. Tract health. Fructooligosaccharides (FOS) are considered a soluble fiber and pre-biotic that support the growth of beneficial bacteria. Since FOS is not digested it increases the material in the digestive tract and promotes regularity.

L-Glutamine is a key component in the maintenance of healthy intestinal mucosa. It fuels intestinal cells and maintains villi. A lack of glutamine may lead to a loss of enterocyte (cells in the small intestine) integrity in the lining of the intestines, which may affect digestion and absorption or allow pathogens into the body.

Olive Leaf Extract works directly against unwanted materials by stimulating your own protective cells (phagocytes) to ingest them without suppressing the immune system or damaging the body’s beneficial flora. Spirulina supports healthy functioning of the liver and immune system, to aid in detoxification.